This rabbit IgG polyclonal antibody was generated against the disintegrin/cysteine-rich/EGF repeat domain of ADAM15 and recognizes the disintegrin/cysteine-rich/EGF repeat domain of mouse ADAM15.
The ADAM (A Disintegrin And Metalloprotease Domain) family is a unique group of proteins that has the ability to cleave or shed extracellular portions of transmembrane proteins. In addition, ADAMs are involved in cell-cell and cell-matrix interactions (e.g., fertilization, muscle development and neurogenesis).
ADAM15 (Metargidin) is a membrane-anchored glycoprotein that has been implicated in pathological neovascularization and prostate cancer metastasis.
From the laboratory of Carl P. Blobel, MD, PhD, Hospital for Special Surgery.
Part of The Investigator's Annexe program.
Product Type: | Antibody |
Antigen: | ADAM15 Disintegrin/Cysteine-rich/EGF repeat domain |
Accession ID: | Q13444 |
Molecular Weight: | ~100 kDa |
Isotype: | IgG |
Clonality: | Polyclonal |
Reactivity: | Mouse |
Immunogen: | Disintegrin domain, cysteine-rich region and an epidermal growth factor (EGF) repeat from mouse ADAM15 |
Species Immunized: | Rabbit |
Epitope: | Disintegrin domain, cysteine-rich region and an EGF repeat |
Purification Method: | Serum, not purified |
Tested Applications: | WB |
Storage: | -80C |
Shipped: | Dry ice |
Antibody | Species Reactivity | Specificity |
ADAM9 | Human | Cytoplasmic Domain |
ADAM9 | Mouse | Cytoplasmic Domain |
ADAM12 | Mouse | Cytoplasmic Domain |
ADAM15 | Human | Cytoplasmic Domain |
ADAM15 | Mouse | Cytoplasmic Domain |
ADAM15 | Human | Extracellular Domain |
ADAM15 | Mouse | Disintegrin Domain |
ADAM17 | Mouse | Cytoplasmic Domain |
ADAM17 | Mouse | Pro domain |
ADAM19 | Mouse | Cytoplasmic Domain |
ADAM28 | Mouse | Cytoplasmic Domain |
ADAM28 | Mouse | Extracellular Domain |
SNX9 | Mouse | Cytoplasmic Domain |
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