Cy5 - TCO
A TCO-activated Cy5 dye for chemoselective labeling and detection of TCO-tagged molecules.
A TCO-activated Cy5 probe can be used for detection and visualization of tetrazine-containing molecules. TCO moiety reacts with tetrazines to produce a stable, covalent linkage, also referred to as the inverse-electron demand Diels-Alder cycloaddition reaction. This reaction is extremely fast (k > 800 M-1s-1), selective, and biocompatible. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
A TCO-activated Cy5 dye for chemoselective labeling and detection of TCO-tagged molecules.
A TCO-activated Cy5 probe can be used for detection and visualization of tetrazine-containing molecules. TCO moiety reacts with tetrazines to produce a stable, covalent linkage, also referred to as the inverse-electron demand Diels-Alder cycloaddition reaction. This reaction is extremely fast (k > 800 M-1s-1), selective, and biocompatible. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Small Molecule |
| Name: | Cy5-TCO |
| Chemical Formula: | C45H60N4O12S3(protonated) |
| Molecular Weight: | 943.16 (protonated) |
| Extinction Coefficient: | 251000 M-1cm-1 |
| Variant MPN: | 1089 |
| Format: | Blue solid |
| Solubility: | Water, DMSO, DMF, MeOH |
| Spectral Information: | Abs/Em = 647/663 nm |
| Comments: | CF280: 0.05; CF260: 0.05 |
| Storage: | -20C. Desiccate |
| Shipped: | Frozen - Dry Ice |
1. Lueckgen A, Garske DS, Ellinghaus A, Mooney DJ, Duda GN, Cipitria A. Dual alginate crosslinking for local patterning of biophysical and biochemical properties [published online ahead of print, 2020 Jul 28]. Acta Biomater. 2020;S1742-7061(20)30433-5. View article
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