Anti-Integrin Alpha-IIb (GPIIb, CD41), Calf-2 Light Chain [MBC 314.5] Antibody
![Anti-Integrin Alpha-IIb (GPIIb, CD41), Calf-2 Light Chain [MBC 314.5] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/913_200120200126269120.jpg "Anti-Integrin Alpha-IIb (GPIIb, CD41), Calf-2 Light Chain [MBC 314.5] Antibody")
This IgG2a mouse monoclonal (MBC 314.5) was generated against glycoprotein IIb and is specific for the calf 2 light chain of human glycoprotein IIb.
Highlights:
- Reacts with human glycoprotein IIb
- Suitable for reduced and non reduced Western Blot, Flow Cytometry and ELISA
Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
From the laboratory of Richard H. Aster, MD, PhD, Blood Center of Wisconsin.
This IgG2a mouse monoclonal (MBC 314.5) was generated against glycoprotein IIb and is specific for the calf 2 light chain of human glycoprotein IIb.
Highlights:
- Reacts with human glycoprotein IIb
- Suitable for reduced and non reduced Western Blot, Flow Cytometry and ELISA
Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
From the laboratory of Richard H. Aster, MD, PhD, Blood Center of Wisconsin.
Specifications
| Product Type: | Antibody |
| Antigen: | Glycoprotein IIb |
| Accession ID: | P08514 |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | MBC 314.5 |
| Reactivity: | Human |
| Immunogen: | Calf 2 light chain |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Method Used to Determine Concentration: | BCA |
| Buffer: | PBS |
| Tested Applications: | WB reduced and non-reduced, Flow Cytometry (0.02 mg/mL), ELISA capture (10ug/mL) and detection (10ug/mL) |
| Concentration: | 1mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
Research
| Antibody | Domain |
| Anti-Integrin Alpha-IIb (GPIIb, CD41) [MBC 132.1] | Glycoprotein IIb |
| Anti-Integrin Alpha-IIb (GPIIb, CD41), Beta Propeller Domain [MBC 290.5] | Beta propeller |
| Anti-Integrin Alpha-IIb (GPIIb, CD41), Calf-1 Domain [MBC 370.2] | Calf 1 |
| Anti-Integrin Alpha-IIb (GPIIb, CD41), Calf-2 Light Chain [MBC 314.5] | Calf 2- light chain |
| Anti-Integrin Beta 3 (GPIIIa, CD61) [MBC 319.4] | EGF repeats |
| Anti-Integrin Beta 3 (GPIIIa, CD61), PSI Domain [AP-3] | PSI/Hybrid amino acids 50-62 |
| Anti-Integrin Beta 3 (GPIIIa, CD61) [MBC 322.8] | EGF repeats |
| Anti-Integrin Beta 3 (GPIIIa, CD61), PSI Domain [AP-5] | PSI amino acids 1-6 |
| Anti-Glycoprotein GPIIIa/GPIIb Complex [AP-2] | Beta 1 |
Provider
From the laboratory of Richard H. Aster, MD, PhD, Blood Center of Wisconsin
References
If you publish research with this product, please let us know so we can cite your paper.
