Alkynyl Secosterol B
Alkynyl secosterol B, a cholesterol ozonolysis product, is a surrogate for the natural sterol. It is formed upon aldol condensation of secosterol A. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Alkynyl secosterol B, a cholesterol ozonolysis product, is a surrogate for the natural sterol. It is formed upon aldol condensation of secosterol A. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Specifications
| Product Type: | Small Molecule |
| Name: | Alkynyl Secosterol B |
| Chemical Formula: | C26H40O3 |
| Molecular Weight: | 400.60 kDa |
| Format: | Solid |
| Purity: | >95%, NMR |
| Solubility: | CHCl3, THF, CH3CN, DMSO |
| Spectral Information: | 1H, 13C NMR |
| Storage: | -20C |
| Shipped: | Ambient temperature |
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
- Windsor, K, Genaro-Mattos, TC, Miyamoto, S, Stec, DF, Kim, HY, Tallman, KA, Porter, NA. Assay of Protein and Peptide Adducts of Cholesterol Ozonolysis Products by Hydrophobic and Click Enrichment Methods. Chem. Res. Toxicol. 2014, 27, 1757.
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