Anti-Psittacine Beak and Feather Disease (PBFD) Virus [15H8] Antibody
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This mouse IgG monoclonal antibody was generated against DNA virus (Circoviridea) and recognizes psittacine beak and feather disease virus (PBFD).
Highlights:
- Reacts with PBFD
- Useful research tool involving other avian circoviruses
- Binds strongly with PBFD
- Does not induce hemagglutination inhibition, possibly signaling the potential for the development of therapeutic measures, as a coadjuvant
- Suitable for ELISA, Dot-immunoblotting, Hemagglutination inhibition (HI, negative for HI) and Immunohistochemical applications
Psittacine beak and feather disease (PBFD) or Beak and feather disease virus (BFDV) is a circular or icosahedral, 14-16 nm diameter, single-stranded circular DNA, non-enveloped virus with a genome size of between 1992 and 2018 nucleotides. PBFDV is now considered a Global Invasive Species, affecting birds in Africa, Oceania, Asia, Europe and North and South Americas, Pacific Islands and a variant of the virus appears to infect lories and similar circoviruses have been identified in doves, pigeons, gulls, geese, canaries and finches. Symptoms include irreversible loss of feathers, shedding of developing feathers, development of abnormal feathers, new pinched feathers, and loss of powder down.
From the laboratory of Branson W. Ritchie, DVM, PhD, University of Georgia.
This mouse IgG monoclonal antibody was generated against DNA virus (Circoviridea) and recognizes psittacine beak and feather disease virus (PBFD).
Highlights:
- Reacts with PBFD
- Useful research tool involving other avian circoviruses
- Binds strongly with PBFD
- Does not induce hemagglutination inhibition, possibly signaling the potential for the development of therapeutic measures, as a coadjuvant
- Suitable for ELISA, Dot-immunoblotting, Hemagglutination inhibition (HI, negative for HI) and Immunohistochemical applications
Psittacine beak and feather disease (PBFD) or Beak and feather disease virus (BFDV) is a circular or icosahedral, 14-16 nm diameter, single-stranded circular DNA, non-enveloped virus with a genome size of between 1992 and 2018 nucleotides. PBFDV is now considered a Global Invasive Species, affecting birds in Africa, Oceania, Asia, Europe and North and South Americas, Pacific Islands and a variant of the virus appears to infect lories and similar circoviruses have been identified in doves, pigeons, gulls, geese, canaries and finches. Symptoms include irreversible loss of feathers, shedding of developing feathers, development of abnormal feathers, new pinched feathers, and loss of powder down.
From the laboratory of Branson W. Ritchie, DVM, PhD, University of Georgia.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Antigen: | Psittacine beak and feather disease virus |
| Accession ID: | AY148285, AF311301, AF311302, AY450436 |
| Molecular Weight: | 660 kDa |
| Isotype: | IgG |
| Clonality: | Monoclonal |
| Clone Name: | 15H8.E3 |
| Reactivity: | PBFD virus |
| Immunogen: | DNA virus (Circoviridea) |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Tested Applications: | ELISA, Dot-immunoblotting, Hemagglutination inhibition (HI, negative for HI), IHC |
| Storage: | -80C |
| Shipped: | Dry ice |
Notes:
Will react with PBFD virus up to/slightly below 1:500 Dilution, but 1:50 to 1:200 recommended. Binds strong to antigen.
- Ritchie BW, Niagro FD, Latimer KS, Steffens WL, Pesti D, Aron L, Lukert PD. Production and characterization of monoclonal antibodies to psittacine beak and feather disease virus. J Vet Diagn Invest. 1992 Jan;4(1):13-8.
- Bassami MR, Berryman D, Wilcox GE, Raidal SR. Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus. Virology. 1998 Sep30;249(2):453-9.
- Heath L, Martin DP, Warburton L, Perrin M, Horsfield W, Kingsley C, Rybicki EP, Williamson AL. Evidence of unique genotypes of beak and feather disease virus in southern Africa. J Virol. 2004 Sep;78(17):9277-84.
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