Anti-Chondroitin Sulfate Proteoglycan 4 (CSPG4) [ME313] Antibody
![Anti-Chondroitin Sulfate Proteoglycan 4 (CSPG4) [ME313] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1178_2001202001263711770.jpg "Anti-Chondroitin Sulfate Proteoglycan 4 (CSPG4) [ME313] Antibody")
This mouse IgG1 monoclonal antibody was generated against WM46 melanoma cells and recognizes human chondroitin sulfate proteoglycan 4 (CSPG4).
Highlights:
- Specific for human CSPG4
- Suitable for Western Blot applications
Melanoma-associated chondroitin sulfate proteoglycan, encoded by CSPG4 gene, is a surface marker for melanoma, astrocytoma and a variety of head and neck cancers. CSPG4 stabilizes cell-substratum interactions during early events of malignant melanoma cell growth on basal membrane. CSPG4 is an integral membrane chondroitin sulfate proteoglycan protein, 260 kDa of mass, yet may migrate slower on gels depending on glycosylation status.
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
Part of The Investigator's Annexe program.
This mouse IgG1 monoclonal antibody was generated against WM46 melanoma cells and recognizes human chondroitin sulfate proteoglycan 4 (CSPG4).
Highlights:
- Specific for human CSPG4
- Suitable for Western Blot applications
Melanoma-associated chondroitin sulfate proteoglycan, encoded by CSPG4 gene, is a surface marker for melanoma, astrocytoma and a variety of head and neck cancers. CSPG4 stabilizes cell-substratum interactions during early events of malignant melanoma cell growth on basal membrane. CSPG4 is an integral membrane chondroitin sulfate proteoglycan protein, 260 kDa of mass, yet may migrate slower on gels depending on glycosylation status.
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Alternative Name(s): | Chondroitin sulfate proteoglycan 4,Chondroitin sulfate proteoglycan NG2,Melanoma chondroitin sulfate proteoglycan,Melanoma-associated chondroitin sulfate proteoglycan |
| Antigen: | Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan, CSPG4 |
| Accession ID: | Q6UVK1 |
| Molecular Weight: | 260+ kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | ME31.3 or ME313 |
| Reactivity: | Human |
| Immunogen: | WM46 melanoma cells |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB (1:1000) |
| Storage: | -20C |
| Shipped: | Cold packs |
- Folberg R, Donoso LA, Atkinson BF, Ernst CS, Herlyn M, Arbizo VV. An antimelanoma monoclonal antibody and the histopathology of uveal melanomas. Arch Ophthalmol. 1985 Feb;103(2):275-9. PubMed PMID: 2579631.
If you publish research with this product, please let us know so we can cite your paper.
