Tetrazine-Amine demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. This reagent is supplied as HCl salt for improved stability and easy handling.
Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
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Product Type: | Small Molecule |
Chemical Formula: | C9H9N5 |
CAS number: | 1092689-33-2 |
Molecular Weight: | 187.09 |
Variant MPN: | 1130 |
Format: | Pink solid |
Purity: | >95% (HPLC) |
Solubility: | DMSO, DMF |
Storage: | -20C. Desiccate |
Shipped: | Ambient |
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