Anti-Zika Virus Envelope (E) Protein [D1-4G2-4-15] Antibody
![Anti-Zika Virus Envelope (E) Protein [D1-4G2-4-15] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1376_2001202001264513750.jpg "Anti-Zika Virus Envelope (E) Protein [D1-4G2-4-15] Antibody")
This mouse IgG2a monoclonal antibody was generated against flavivirus envelope proteins and recognizes protein E of Zika virus.
Highlights:
- Recognizes Zika virus
- Suitable for Immunofluorescence applications
Zika virus (ZIKV) is a member of the virus family Flaviviridae and the genus Flavivirus, transmitted by daytime-active Aedes mosquitoes. Zika is related to other mosquito transmitted viruses such as dengue, yellow fever, Japanese encephalitis and west nile. Similar to other flaviviruses, ZIKV is enveloped and icosahedral and has a nonsegmented, single-stranded, positive-sense RNA genome. Common symptoms of infection with the virus include mild headaches, maculopapular rash, fever, malaise, conjunctivitis, and joint pains.
This mouse IgG2a monoclonal antibody was generated against flavivirus envelope proteins and recognizes protein E of Zika virus.
Highlights:
- Recognizes Zika virus
- Suitable for Immunofluorescence applications
Zika virus (ZIKV) is a member of the virus family Flaviviridae and the genus Flavivirus, transmitted by daytime-active Aedes mosquitoes. Zika is related to other mosquito transmitted viruses such as dengue, yellow fever, Japanese encephalitis and west nile. Similar to other flaviviruses, ZIKV is enveloped and icosahedral and has a nonsegmented, single-stranded, positive-sense RNA genome. Common symptoms of infection with the virus include mild headaches, maculopapular rash, fever, malaise, conjunctivitis, and joint pains.
| Product Type: | Antibody |
| Antigen: | Flavivirus Envelope (E) Protein |
| Accession ID: | A0A142I5B9 |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | D1-4G2-4-15 |
| Reactivity: | Virus |
| Immunogen: | Flavivirus envelope proteins |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | PBS, pH 7.2 |
| Tested Applications: | IF |
| Comments: | Derived from strain YYC202, strain has a growth requirement for acetate and isoleucine |
| Storage: | -20C |
| Shipped: | Cold packs |
Detection of ZIKV via immunofluorescence
Sample confocal images of forebrain-specific hNPCs 56 hr after infection with ZIKV supernatant, immunostained for ZIKV envelop protein (ZIKVE; green) and DAPI (gray). Cells were differentiated from the C1-2 hiPSC line. Scale bars, 20 ?m.
Adapted from: Tang H, et al. Cell Stem Cell. 2016 May 5;18(5):587-90.
- Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell Stem Cell. 2016 May 5;18(5):587-90.
- Saver AE, Crawford SA, Joyce JD, Bertke AS. Route of Infection Influences Zika Virus Shedding in a Guinea Pig Model. Cells. 2019;8(11):1437. Published 2019 Nov 14. View article
- Huang Y, Wang Y, Meng S, et al. Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling. Mediators Inflamm. 2020;2020:9527147. Published 2020 Apr 28. View article
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