PBI Sample Prep
PBI Shredder Systems
PBI Shredder Systems are low shear mechanical devices for gentle, rapid, and safe disruption of tissues and organisms. Both The PCT Shredder and The SHREDDER SG3 can provide effective extraction of DNA, RNA, proteins, mitochondria, lipids and small molecules from tissues and organisms, when used with Shredder Tubes and your choice of buffers. Both systems use a variety of Shredder Tubes to directly and rapidly grind solid samples providing easy handling and reducing sample contamination. Additional extraction efficiency can be achieved if this process is combined with pressure cycling technology (PCT)
The PCT Shredder is a mechanical homogenization system for use with tough, fibrous, and other difficult-to-disrupt tissues and organisms. The PCT Shredder is used to rapidly homogenize biological samples directly in Shredder Tubes. This pre-processing method increases sample surface area and, when followed by pressure cycling technology (PCT extraction), permits better access of high pressure extraction fluid to the sample, resulting in improved sample lysis and extraction of the desired analytes.
Shredder Tubes are containers used in the disruption of tough structures such as fibrous muscle tissue, plant cell walls, insect exoskeletons or the cuticle of nematodes, to rapidly achieve excellent yields of high quality nucleic acids, proteins, lipids, and small molecules.
