The Lee Lab has a special interest in emerging viruses, with a focus on molecular viral-host interactions at the level enveloped virus entry and budding mechanisms. They currently use HIV and henipaviruses (a emerging genus of lethal paramyxoviruses) as their primary model systems. In addition, he also has active projects translating insights gained from basic studies on host-pathogen interactions into broad-spectrum anti-viral therapeutics, and has long-standing collaborations with colleagues in medical chemistry. The Lee Lab has access to BSL4 (UTMB-Galveston) facilities for high-containment work on lethal pathogens.