Research in the Monje laboratory focuses on the study of Schwann cells in their dual role of forming a myelin sheath and promoting axon regeneration after injury. They use in vitro cultured Schwann cells as platforms for basic studies aimed at defining the cellular and molecular mechanisms underlaying proliferation, differentiation and myelin formation. They also use cultured Schwann cells in cell therapy strategies for peripheral and central nervous system repair. For her studies, Dr. Monje relies on a combination of cell biology and genomic approaches to address the myelinating and regenerative capabilities of Schwann cells obtained from humans and experimental animals.
*Now affiliated with Indiana University.