Frank I. Comer, PhD, The John Hopkins University

Frank I. Comer, PhD
Frank I. Comer, PhD

Dr. Comer is interested in developing specific antibodies to O-linked N-acetylglucosamine (O-GlcNAc). He also participated in projects aimed at developing the diagnostic potential of O-GlcNAc in disease states such as diabetes.

Products

References

  1. Comer FI, Vosseller K, Wells L, Accavitti MA, Hart GW. Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine. Anal Biochem. 2001 Jun 15;293(2):169-77.
  2. Zachara, Natasha E; Vosseller, Keith; Hart, Gerald W. Detection and analysis of proteins modified by O-linked N-acetylglucosamine. Curr Protoc Protein Sci. 2011 11;Chapter 12:Unit12.8.
  3. Ma J, Hart GW. O-GlcNAc profiling: from proteins to proteomes. Clin Proteomics. 2014 Mar 5;11(1):8. doi: 10.1186/1559-0275-11-8.
  4. Hart GW, Slawson C, Ramirez-Correa G, Lagerlof O. Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu Rev Biochem. 2011;80:825-58.
  5. Hardivillé S, Hart GW. Nutrient regulation of signaling, transcription, and cell physiology by O-GlcNAcylation. Cell Metab. 2014 Aug 5;20(2):208-13.
  6. Comer, F I; Vosseller, K; Wells, L; Accavitti, M A; Hart, G W. Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.