DNA Damage/Repair

Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (exogenous) and internal metabolic (endogenous) processes. Changes to the cellular genome can generate errors in the transcription of DNA and ensuing translation into proteins necessary for signaling and cellular function. Genomic mutations can also be carried over into daughter generations of cells if the mutation is not repaired prior to mitosis.

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Product Type
Antibody 
(30)
Cell Line 
(20)
Kit 
(1)
Protein 
(1)
Small Molecule 
(7)
Virus 
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Species
Homo sapiens 
(6)
Mus musculus 
(1)
Rattus norvegicus 
(1)
Fusion Tag(s)
Mouse Fab version contains His-tag 
(6)
Isotype
Goat IgG 
(1)
IgG 
(2)
IgG1 
(1)
IgG1k 
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IgG2a 
(1)
Mouse IgG2a, rabbit IgG, mouse Fab, goat IgG 
(1)
Mouse Fab 
(1)
Mouse IgG2a 
(1)
Rabbit IgG 
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Organism
Human 
(6)
Mouse 
(5)
Rat 
(1)
Tested Applications
ChIP assay (ideal for ChIP-seq or ChIP-qPCR) 
(3)
ELISA, WB and IP 
(1)
FACS, Immunoprecipitation, Paraffin embedded, WB 
(1)
IP, mobility supershift 
(1)
IP, WB 
(1)
WB 10 μg/mL, ELISA 10 μg/mL, ICC/IF 10 μg/mL 
(1)
WB, ELISA 
(1)
WB, IP 
(14)
Western Blot: 1:500 - 1:1,000; ELISA: 1:2,000 - 1:10,000; ImmunoPrecipitation: 1:500 
(1)
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Selection Gene
Cell selection using hygromycin, dose is cell dependent 
(1)