Anti-Toxoplasma gondii Centrin-1 Antibody
This rabbit polyclonal antibody was generated against full length Toxoplasma gondii Centrin-1 and recognizes for T. gondii Centrin-1.
Highlights:
- Recognizes T. gondii Centrin-1
- Recommended for Immunofluorescence applications
Centrins, also known as caltractins, are a family of calcium-binding phosphoproteins found in the centrosome. Toxoplasma Centrin-1 localizes to the centrosome of both interphase and mitotic cells in the asexual replication cycle, reflecting the dynamic behavior of the centrosome during the cell cycle. Based on its sequence features shared with centrin studied in other systems, TgCentrin-1 is classified as a centriolar centrin.
From the laboratory of Marc-Jan Gubbels, PhD, Boston College.
Part of The Investigator's Annexe program.
This rabbit polyclonal antibody was generated against full length Toxoplasma gondii Centrin-1 and recognizes for T. gondii Centrin-1.
Highlights:
- Recognizes T. gondii Centrin-1
- Recommended for Immunofluorescence applications
Centrins, also known as caltractins, are a family of calcium-binding phosphoproteins found in the centrosome. Toxoplasma Centrin-1 localizes to the centrosome of both interphase and mitotic cells in the asexual replication cycle, reflecting the dynamic behavior of the centrosome during the cell cycle. Based on its sequence features shared with centrin studied in other systems, TgCentrin-1 is classified as a centriolar centrin.
From the laboratory of Marc-Jan Gubbels, PhD, Boston College.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Antigen: | Toxoplasma gondiiCentrin-1 (Caltractin) |
| Accession ID: | Q12798, XP_002367090.1 |
| Molecular Weight: | 19.3 kDa |
| Isotype: | Unknown |
| Clonality: | Polyclonal |
| Reactivity: | Toxoplasma |
| Immunogen: | 6x-His tagged recombinant Toxoplasma gondiiCentrin-1 |
| Species Immunized: | Rabbit |
| Purification Method: | Affinity purified against the recombinant protein cross-linked to cyanogen bromide Sepharose 4B |
| Buffer: | PBS with 1% BSA and 0.02% Na-azide |
| Tested Applications: | IF (1,1000) |
| Storage: | -20C |
| Shipped: | Cold packs |
- Fung C, Beck JR, Robertson SD, Gubbels MJ, Bradley PJ. Toxoplasma ISP4 is a central IMC sub-compartment protein whose localization depends on palmitoylation but not myristoylation. Mol Biochem Parasitol. 2012 Aug;184(2):99-108.
- Gavelis GS, Herranz M, Wakeman KC, Ripken C, Mitarai S, Gile GH, Keeling PJ, Leander BS. Dinoflagellate nucleus contains an extensive endomembrane network, the nuclear net. Sci Rep. 2019 Jan 29;9(1):839. View Article
- Tosetti N, Dos Santos Pacheco N, Soldati-Favre D, Jacot D. Three F-actin assembly centers regulate organelle inheritance, cell-cell communication and motility in Toxoplasma gondii. Elife. 2019 Feb 12;8. pii: e42669. View Article
- Srivastava S, White MW, Sullivan WJ Jr. Toxoplasma gondii AP2XII-2 Contributes to Proper Progression through S-Phase of the Cell Cycle. mSphere. 2020 Sep 16;5(5):e00542-20. View article
- Bansal P, Antil N, Kumar M, Yamaryo-Botté Y, Rawat RS, Pinto S, Datta KK, Katris NJ, Botté CY, Prasad TSK, Sharma P. Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii. PLoS Pathog. 2021 Feb 26;17(2):e1009325. View article
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