Anti-Lipoprotein I (LpI) [11A8.A7] Antibody
![Anti-Lipoprotein I (LpI) [11A8.A7] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1415_2001202001264614140.jpg "Anti-Lipoprotein I (LpI) [11A8.A7] Antibody")
This mouse IgM monoclonal antibody was generated against lipoprotein and recognizes Callinectes sapidus (blue crab) (and possibly multiple other crustaceans) Crustacean Lipoprotein I (LpI).
Highlights:
- Recognizes Callinectes sapidus (blue crab) (and possibly multiple other crustaceans) Crustacean LpI
- May react with a broader spectrum of Lps from crustaceans
- May be especially useful in the study of crustaceans immunological response to, e.g., environmental stress and disease.
- Suitable for Immunofluorescence, Western Blot and ELISA applications
A lipoprotein is a biochemical assembly whose purpose is to transport hydrophobic lipid molecules in water, as in blood or ECF. Specifically LPI is in the hemolymph of crustaceans and transports lipid to peripheral tissues and also has a role in crustacean immune recognition. LpI was first found in stage 5 embryos and appeared to be synthesized by lateral basophilic cuboidal cells that demonstrated cytoplasmic immunoreactivity for LpI at their interface with the yolk mass. The embryonic cuboidal cells bore a strong cytologic resemblance to the hepatopancreas cells of later stages (zoea, megalopae, adults), which were also immunoreactive for LpI.
From the laboratory of
Richard F. Lee, PhD, Skidaway Institute of Oceanography, Department of Marine Sciences at University of Georgia.
This mouse IgM monoclonal antibody was generated against lipoprotein and recognizes Callinectes sapidus (blue crab) (and possibly multiple other crustaceans) Crustacean Lipoprotein I (LpI).
Highlights:
- Recognizes Callinectes sapidus (blue crab) (and possibly multiple other crustaceans) Crustacean LpI
- May react with a broader spectrum of Lps from crustaceans
- May be especially useful in the study of crustaceans immunological response to, e.g., environmental stress and disease.
- Suitable for Immunofluorescence, Western Blot and ELISA applications
A lipoprotein is a biochemical assembly whose purpose is to transport hydrophobic lipid molecules in water, as in blood or ECF. Specifically LPI is in the hemolymph of crustaceans and transports lipid to peripheral tissues and also has a role in crustacean immune recognition. LpI was first found in stage 5 embryos and appeared to be synthesized by lateral basophilic cuboidal cells that demonstrated cytoplasmic immunoreactivity for LpI at their interface with the yolk mass. The embryonic cuboidal cells bore a strong cytologic resemblance to the hepatopancreas cells of later stages (zoea, megalopae, adults), which were also immunoreactive for LpI.
From the laboratory of Richard F. Lee, PhD, Skidaway Institute of Oceanography, Department of Marine Sciences at University of Georgia.
| Product Type: | Antibody |
| Antigen: | Crustacean Lipoprotein I (LpI) |
| Molecular Weight: | ~224 kDa |
| Isotype: | IgM |
| Clonality: | Monoclonal |
| Clone Name: | 11A8.A7 |
| Reactivity: | Callinectes sapidus (blue crab). Possibly multiple other crustaceans |
| Immunogen: | Lipoprotein |
| Species Immunized: | Mouse |
| Buffer: | Cell Culture Supernatant |
| Tested Applications: | ELISA, WB, IF |
| Storage: | -80C |
| Shipped: | Cold Packs |
- Walker A, Ando S, Lee RF. Synthesis of a high-density lipoprotein in the developing blue crab (Callinectes sapidus). Biol Bull. 2003 Feb;204(1):50-6.
- Walker A, Lee RF. Lipovitellin and Lipid Droplet Accumulation in Oocytes During Ovarian Maturation in the Blue Crab, Callinectes sapidus. Experimental Zoology. 1995: 271:401-412
- Rehn KG, Lee RF. Lipophorin as a lipid carrier in the hemolymph of the horseshoe crab, Limulus polyphemus. Braz J Med Biol Res. 1994 May;27(5):1135-9.
If you publish research with this product, please let us know so we can cite your paper.
