Anti-VGLUT2/SLC17A6 (Rabbit) Antibody
This rabbit IgG polyclonal antibody was generated against the C-terminus of vesicular glutamate transporter 2 (VGLUT2) GST-fusion protein and recognizes mouse and rat VGLUT2.
Highlights:
- Recognizes mouse and rat VGLUT2
- Suitable for Immunohistochemistry, Immunocytochemistry and Western Blot applications
VGLUT2 also known as SLC17A6 is a vesicle-bound, sodium-dependent phosphate transporter that is expressed in the neuron-rich regions of the brain. It facilitates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.
From the laboratory of Jeffrey D. Erickson, PhD, LSU Health Sciences Center New Orleans.
This rabbit IgG polyclonal antibody was generated against the C-terminus of vesicular glutamate transporter 2 (VGLUT2) GST-fusion protein and recognizes mouse and rat VGLUT2.
Highlights:
- Recognizes mouse and rat VGLUT2
- Suitable for Immunohistochemistry, Immunocytochemistry and Western Blot applications
VGLUT2 also known as SLC17A6 is a vesicle-bound, sodium-dependent phosphate transporter that is expressed in the neuron-rich regions of the brain. It facilitates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.
From the laboratory of Jeffrey D. Erickson, PhD, LSU Health Sciences Center New Orleans.
Specifications
| Product Type: | Antibody |
| Accession ID: | Q9P2U8 |
| Antigen: | C-terminus VGLUT2 |
| Molecular Weight: | 36 kDa |
| Clonality: | Polyclonal |
| Clone Name: | VGLUT2 |
| Reactivity: | Mouse, Rat |
| Immunogen: | C-terminus of VGLUT2 (GST-fusion protein) |
| Species Immunized: | Rabbit |
| Tested Applications: | WB, IHC, ICC 1:2000 |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Jeffrey D. Erickson, PhD, LSU Health Sciences Center New Orleans.
References
- Varoqui H, Erickson JD. Selective up-regulation of system a transporter mRNA in diabetic liver. Biochem Biophys Res Commun. 2002 Jan 25;290(3):903-8. PubMed PMID: 11798158.
- He H, Mahnke AH, Doyle S, Fan N, Wang CC, Hall BJ, Tang YP, Inglis FM, Chen C, Erickson JD. Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning. J Neurosci. 2012 Nov 7;32(45):15886-901.
- Doyle S, Pyndiah S, De Gois S, Erickson JD. Excitation-transcription coupling via calcium/calmodulin-dependent protein kinase/ERK1/2 signaling mediates the coordinate induction of VGLUT2 and Narp triggered by a prolonged increase in glutamatergic synaptic activity. J Biol Chem. 2010 May 7;285(19):14366-76.
- De Gois S, Schäfer MK, Defamie N, Chen C, Ricci A, Weihe E, Varoqui H, Erickson JD. Homeostatic scaling of vesicular glutamate and GABA transporter expression in rat neocortical circuits. J Neurosci. 2005 Aug 3;25(31):7121-33. PubMed PMID: 16079394.
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