Anti-PRKAA1/2 [84.1.1] Antibody
![Anti-PRKAA1/2 [84.1.1] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1570_2001202001265315690.jpg "Anti-PRKAA1/2 [84.1.1] Antibody")
This mouse monoclonal antibody was generated against a peptide corresponding to the α1/α2 kinase domain of protein kinase AMP-activated catalytic subunit alpha 1/2 (PRKAA1/2) and recognizes Drosophila, mouse, rat, and human PRKAA1/2.
Highlights:
- Reacts with Drosophila, mouse, rat, and human PRKAA1/2
- Suitable for Western Blot, ELISA, ICC//IF, IHC-Fr, and IP applications
PRKAA1/2 belong to the Serine/Threonine protein kinase family and the catalytic subunit of the 5'-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
From the laboratory of Jay E. Brenman, PhD, University of North Carolina Chapel Hill.
This mouse monoclonal antibody was generated against a peptide corresponding to the α1/α2 kinase domain of protein kinase AMP-activated catalytic subunit alpha 1/2 (PRKAA1/2) and recognizes Drosophila, mouse, rat, and human PRKAA1/2.
Highlights:
- Reacts with Drosophila, mouse, rat, and human PRKAA1/2
- Suitable for Western Blot, ELISA, ICC//IF, IHC-Fr, and IP applications
PRKAA1/2 belong to the Serine/Threonine protein kinase family and the catalytic subunit of the 5'-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
From the laboratory of Jay E. Brenman, PhD, University of North Carolina Chapel Hill.
| Product Type: | Antibody |
| Antigen: | AMP-Activated Protein Kinase α1/α2, AMPKα, PRKAA1, PRKAA2 |
| Accession ID: | Q13131, P54646 |
| Molecular Weight: | 63 kDa |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 84.1.1 |
| Reactivity: | Drosophila, mouse, rat, human |
| Immunogen: | Peptide |
| Species Immunized: | Mouse |
| Epitope: | 29 amino acids (from Drosophila α1/α2 kinase domain) |
| Buffer: | Cell culture supernatant |
| Tested Applications: | WB (1:100-1:1,000), ELISA, ICC/IF, IHC-Fr, IP |
| Storage: | -80C |
| Shipped: | Cold Packs |
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