Anti-Nidogen, G1/Link Region [4H5-B2-E4] Antibody
![Anti-Nidogen, G1/Link Region [4H5-B2-E4] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1621_2001202001265516200.jpg "Anti-Nidogen, G1/Link Region [4H5-B2-E4] Antibody")
This rat IgG2a monoclonal antibody was generated against G1/link region of mouse nidogen and recognizes nidogen.
Highlights:
- Reacts with nidogen
- Able to block nidogen binding to laminin
- Suitable for Western Blot and ELISA applications
Nidogens, formerly known as entactins, are a family of sulfated monomeric glycoproteins located in the basal lamina. There are two types, nidogen-1 (NID1) and nidogen-2 (NID2). The basement membrane protein, nidogen-1, was previously shown to consist of three globular domains, G1 to G3, and two connecting segments. Nidogen-1 is a major mediator in the formation of ternary complexes with laminins, collagen IV, perlecan and fibulins. Nidogens have been shown to play a role in cardiac and lung development.
From the laboratory of Jay W. Fox, PhD, University of Virginia.
This rat IgG2a monoclonal antibody was generated against G1/link region of mouse nidogen and recognizes nidogen.
Highlights:
- Reacts with nidogen
- Able to block nidogen binding to laminin
- Suitable for Western Blot and ELISA applications
Nidogens, formerly known as entactins, are a family of sulfated monomeric glycoproteins located in the basal lamina. There are two types, nidogen-1 (NID1) and nidogen-2 (NID2). The basement membrane protein, nidogen-1, was previously shown to consist of three globular domains, G1 to G3, and two connecting segments. Nidogen-1 is a major mediator in the formation of ternary complexes with laminins, collagen IV, perlecan and fibulins. Nidogens have been shown to play a role in cardiac and lung development.
From the laboratory of Jay W. Fox, PhD, University of Virginia.
| Product Type: | Antibody |
| Antigen: | Nidogen |
| Accession ID: | P14543 |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 4H5-B2-E4 |
| Immunogen: | G1/link region of mouse nidogen |
| Species Immunized: | Rat |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, ELISA |
| Storage: | -20C |
| Shipped: | Cold Packs |
- Ries A, Göhring W, Fox JW, Timpl R, Sasaki T. Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies. Eur J Biochem. 2001 Oct;268(19):5119-28. PubMed PMID: 11589703.
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