Anti-Hemojuvelin (HFE2) Antibody
This rabbit polyclonal antibody was generated against GST-fusion protein containing a 77 amino acid region of mouse hemojuvelin (HJV) and recognizes human and mouse HJV.
Highlights:
- Reacts with human and mouse HFE2
- Binds to the epitope RQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFD
- Suitable for Western Blot applications
Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a member of the repulsive guidance molecule family of proteins. The protein in mammals is membrane-bound and soluble and is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a severe form of hemochromatosis.
From the laboratory of Kostas Pantopoulos, PhD, McGill University.
This rabbit polyclonal antibody was generated against GST-fusion protein containing a 77 amino acid region of mouse hemojuvelin (HJV) and recognizes human and mouse HJV.
Highlights:
- Reacts with human and mouse HFE2
- Binds to the epitope RQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFD
- Suitable for Western Blot applications
Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a member of the repulsive guidance molecule family of proteins. The protein in mammals is membrane-bound and soluble and is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a severe form of hemochromatosis.
From the laboratory of Kostas Pantopoulos, PhD, McGill University.
Specifications
| Product Type: | Antibody |
| Antigen: | Mouse HFE2 |
| Accession ID: | Q7TQ32, Q6ZVN8 |
| Molecular Weight: | 50 kDa |
| Clonality: | Polyclonal |
| Reactivity: | Human and Mouse |
| Immunogen: | GST-fusion protein containing a 77 amino acid region of mouse HFE2 |
| Species Immunized: | Rabbit |
| Epitope: | RQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFD |
| Purification Method: | To remove antibodies that were generated against the GST moiety, serum was purified by absorption through an affinity column of immobilized GST (Pierce) |
| Buffer: | Serum with 0.05% sodium azide |
| Tested Applications: | WB (1:2000) |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Kostas Pantopoulos, PhD, McGill University.
References
If you publish research with this product, please let us know so we can cite your paper.
