Rat Retinal Pigment Epithelium Cell Line (BPEI-1)
Spontaneously arising cell line of rat pigment epithelial cells (RPE) named BPEI-1 with RPE-specific features.
Highlights:
- Cells express cytokeratin and cellular retinaldehyde binding protein (RLBP1)
- Cells have the ability to phagocytize photoreceptor outer segments.
The pigmented layer of retina or retinal pigment epithelium (RPE) is a monolayer of pigmented cells situated between the neuroretina and the choroids. There are a few main functions of the RPE, including transport of nutrients, absorption of light, phagocytosis of shed photoreceptor membranes, and secretion of essential factors for the structural integrity of the retina. Research has shown that the RPE is where macular degeneration begins.
From the laboratory of George Inana, MD, PhD, University of Miami.
Spontaneously arising cell line of rat pigment epithelial cells (RPE) named BPEI-1 with RPE-specific features.
Highlights:
- Cells express cytokeratin and cellular retinaldehyde binding protein (RLBP1)
- Cells have the ability to phagocytize photoreceptor outer segments.
The pigmented layer of retina or retinal pigment epithelium (RPE) is a monolayer of pigmented cells situated between the neuroretina and the choroids. There are a few main functions of the RPE, including transport of nutrients, absorption of light, phagocytosis of shed photoreceptor membranes, and secretion of essential factors for the structural integrity of the retina. Research has shown that the RPE is where macular degeneration begins.
From the laboratory of George Inana, MD, PhD, University of Miami.
Specifications
| Product Type: | Cell Line |
| Cell Type: | Retinal pigment epithelium |
| Accession ID: | CVCL_DF63 |
| Morphology: | Epithelial to fibroblastic |
| Source: | Rat eye/RPE |
| Organism: | Rat |
| Biosafety Level: | BSL 1 |
| Growth Conditions: | MEM with 20% FBS or MEM with 5% FBS |
| Subculturing: | Multiple times, 18h doubling time in MEM 20% FBS |
| Cryopreservation: | 10% DMSO and 90% FBS |
| Storage: | LN2 |
| Shipped: | Dry Ice |
Provider
From the laboratory of George Inana, MD, PhD, University of Miami.
References
- McLaren MJ, Sasabe T, Li CY, Brown ME, Inana G. Spontaneously arising immortal cell line of rat retinal pigmented epithelial cells. Exp Cell Res. 1993 Feb;204(2):311-20.
If you publish research with this product, please let us know so we can cite your paper.
