Canine Osteosarcoma Cell Line (OSCA-71)
OSCA-71 is a canine osteosarcoma cell line derived from a tumor of a 7-year old female Golden Retriever.
Highlights:
- Gene expression profile is consistent with that observed in more aggressive molecular phenotype of osteosarcoma
Osteosarcomas are aggressive malignant neoplasia that arise from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and exhibit osteoblastic differentiation and produce malignant osteoid.
From the laboratory of Jaime F. Modiano, VMD, PhD, University Minnesota, Twin Cities.
OSCA-71 is a canine osteosarcoma cell line derived from a tumor of a 7-year old female Golden Retriever.
Highlights:
- Gene expression profile is consistent with that observed in more aggressive molecular phenotype of osteosarcoma
Osteosarcomas are aggressive malignant neoplasia that arise from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and exhibit osteoblastic differentiation and produce malignant osteoid.
From the laboratory of Jaime F. Modiano, VMD, PhD, University Minnesota, Twin Cities.
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Specifications
| Product Type: | Cell Line |
| Name: | OSCA-71 |
| Cell Type: | Osteosarcoma |
| Accession ID: | CVCL_L400 |
| Morphology: | Spindle |
| Source: | Bone |
| Organism: | Dog |
| Biosafety Level: | 2 |
| Growth Conditions: | DMEM, 10mM HEPES, 10% FBS, 100ug/mL Primocin |
| Subculturing: | Doubling time approx. 1 day |
| Cryopreservation: | 90%FBS/10% DMSO |
| Mycoplasma Tested: | Yes |
| Storage: | Liquid nitrogen |
| Shipped: | Dry Ice |
Documentation
Provider
From the laboratory of Jaime F. Modiano, VMD, PhD, University Minnesota, Twin Cities.
References
- Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 2011 Sep;49(3):356-67.
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