RPE is a highly selective, sensitive and reversible off-on fluorescent Fe3+ sensor which can selectively image native Fe3+ in live cells.
Highlights:
RPE is a highly sensitive, highly selective and reversible turn-on fluorescent Fe3+ sensor. The sensor readily detects endogenous chelatable Fe3+ in live human SH-SY5Y cells at subcellular resolution in real time. The sensor gives a distinct rapid and reversible fluorescence response upon the alteration of intracellular Fe3+ levels with little interference from other biologically relevant metal ions.
From the laboratory of Maolin Guo, PhD, University of Massachusetts Dartmouth.
Product Type: | Small Molecule |
Name: | Methyl 6-(3',6'-bis(diethylamino)-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)picolinate (RPE) |
Chemical Formula: | C35H36N4O4 |
Molecular Weight: | 576 |
Format: | Off-white solid |
Purity: | >95% |
Solubility: | DMSO, DMF, EtOH, ACN, etc. |
Spectral Information: | NMR, MS |
Platform: | Fluorescence microscope |
Compatible Cells: | Mammalian cells |
Detection Method: | Fluorescence (excitation: 510-580 nm; emission: 550-700 nm) |
Comments: | Avoid exposure to light; Suggested amount per experiment: 10 μM (or 0.1 μg) |
Storage: | -20C to -80C |
Shipped: | Dry ice |
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