Anti-Heat-Labile Enterotoxin (HLT) LT-IIa Antibody
This rabbit polyclonal antibody was raised against protein and recognizes His-tagged LT-IIa, a type II heat-labile enterotoxin of Escherichia coli.
Highlights:
- Recognize both the A and B subunits of the toxin LT-IIa, a type II heat-labile enterotoxin
- Suitable for Western Blot and ELISA applications
LT-IIa is a type II heat-labile enterotoxin produced by certain strains of Escherichia coli. The enterotoxin binds to GD1b, GD1a, GM1, and to several other gangliosides on the cell surface. The molecule induces high levels of cAMP in the cell upon intoxication. The molecule is also a very strong mucosal and systemic adjuvant when administered by peritoneal, intranasal, or intradermal routes.
From the laboratory of Terry D. Connell, PhD, University at Buffalo.
This rabbit polyclonal antibody was raised against protein and recognizes His-tagged LT-IIa, a type II heat-labile enterotoxin of Escherichia coli.
Highlights:
- Recognize both the A and B subunits of the toxin LT-IIa, a type II heat-labile enterotoxin
- Suitable for Western Blot and ELISA applications
LT-IIa is a type II heat-labile enterotoxin produced by certain strains of Escherichia coli. The enterotoxin binds to GD1b, GD1a, GM1, and to several other gangliosides on the cell surface. The molecule induces high levels of cAMP in the cell upon intoxication. The molecule is also a very strong mucosal and systemic adjuvant when administered by peritoneal, intranasal, or intradermal routes.
From the laboratory of Terry D. Connell, PhD, University at Buffalo.
Specifications
| Product Type: | Antibody |
| Antigen: | LT-lla |
| Accession ID: | JQ031711.1 |
| Molecular Weight: | 88 kDa |
| Clonality: | Polyclonal |
| Immunogen: | Protein |
| Species Immunized: | Rabbit |
| Buffer: | Antiserum |
| Tested Applications: | WB (1:5,000 - 1:20,000) |
| Comments: | Hyperimmune antiserum |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Terry D. Connell, PhD, University at Buffalo.
References
- Hesham F. Nawar, Sergio Arce, Michael W. Russell and Terry D. Connell. 2005. Mucosal Adjuvant Properties of Mutant LT-IIa and LT-IIb Enterotoxins That Exhibit Altered Ganglioside-Binding Activities. Infect. Immun. 73(3):1330-1342.
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