Anti-Caspase 10 [25C2] Antibody
This IgG2a rat monoclonal antibody was generated against the bacterial fusion protein p20 and recognizes human caspase 10.
Caspase 10, an enzyme encoded by the CASP10 gene in humans, is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases is critical for cell apoptosis. Caspase 10 cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
From a laboratory at Harvard University.
Part of The Investigator's Annexe program.
This IgG2a rat monoclonal antibody was generated against the bacterial fusion protein p20 and recognizes human caspase 10.
Caspase 10, an enzyme encoded by the CASP10 gene in humans, is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases is critical for cell apoptosis. Caspase 10 cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
From a laboratory at Harvard University.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Name: | Anti-Caspase 10 (25C2) |
| Accession ID: | Q92851 |
| Host: | Rat |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 25C2 |
| Specificity: | Caspase 10 (human) |
| Immunogen: | Bacterial fusion protein (p20) |
| Format: | Liquid |
| Purification Method: | Protein G affinity purified |
| Tested Applications: | WB, ELISA |
| Concentration: | 1mg/mL |
| Amount: | 100uL |
| Storage: | Store at 4C |
| Shipped: | Cold packs |
Provider
From a laboratory at Harvard University.
References
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