Anti-c-Myc [9E11] Antibody
This mouse IgG2a monoclonal antibody recognizes human c-Myc and was generated against a synthetic peptide corresponding to residues 408-420 of human c-Myc.
The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients. Myc (c-Myc) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Mutated c-myc leads to the unregulated expression of many genes, some of which are involved in cell proliferation and results in the formation of cancer.
From a laboratory at Cancer Research Technology.
Part of The Investigator's Annexe program.
This mouse IgG2a monoclonal antibody recognizes human c-Myc and was generated against a synthetic peptide corresponding to residues 408-420 of human c-Myc.
The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients. Myc (c-Myc) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Mutated c-myc leads to the unregulated expression of many genes, some of which are involved in cell proliferation and results in the formation of cancer.
From a laboratory at Cancer Research Technology.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Name: | Anti c-Myc (9E11) monoclonal antibody |
| Accession ID: | P01106 |
| Host: | Balb/c |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 9 E11 |
| Specificity: | Human |
| Immunogen: | Residues 408-420. AEEQKLISEEDL. |
| Format: | Liquid |
| Purification Method: | Protein G purified |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | Frozen, Immunoprecipitation, Paraffin embedded |
| Concentration: | 1mg/mL |
| Amount: | 100uL |
| Storage: | Store at 4C |
| Shipped: | Cold packs |
- Halme A, Bumgarner S, Styles C, Fink GR. Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. 2004. Cell. 116(3):405-15. PMID: 15016375
- Kari B, Lussenhop N, Goertz R, Wabuke-Bunoti M, Radeke R, Gehrz R. Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes. 1986. J. Virol. 60:345-352. PMID: 3021969
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