Xenopus UCN1 Antibodies
![Anti-Xenopus UCN1 [#3464] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-Xenopus UCN1 [#3464] Antibody")
These rabbit IgG polyclonal antibodies were raised against urocortin 1 (xUCN1) conjugated to keyhole limpet hemocyanin (KLH) and recognize xenopus UCN1.
Highlights:
- Reacts with xenopus UCN1
- Suitable for Immunohistochemistry applications
Urocortin belongs to the corticotropin-releasing factor (CRF) family of proteins which includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is involved in the mammalian stress response, and regulates aspects of appetite and stress response. Urocortin has cardiovascular effects including increasted heart rate and coronary blood flow.
From the laboratory of Robert J. Denver, PhD, University of Michigan.
These rabbit IgG polyclonal antibodies were raised against urocortin 1 (xUCN1) conjugated to keyhole limpet hemocyanin (KLH) and recognize xenopus UCN1.
Highlights:
- Reacts with xenopus UCN1
- Suitable for Immunohistochemistry applications
Urocortin belongs to the corticotropin-releasing factor (CRF) family of proteins which includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is involved in the mammalian stress response, and regulates aspects of appetite and stress response. Urocortin has cardiovascular effects including increasted heart rate and coronary blood flow.
From the laboratory of Robert J. Denver, PhD, University of Michigan.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Antibody |
| Antigen: | Xenopus urocortin 1 (xUCN1) |
| Accession ID: | P55089 |
| Molecular Weight: | 5 kDa |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Clone Name: | 3465 or 3465 |
| Reactivity: | Anuran amphibians, possibly others |
| Immunogen: | xUCN1 conjugated to keyhole limpet hemocyanin (KLH), amino acid sequence CQMIEIAKTQNQKQQAEQNRIIFDSV |
| Species Immunized: | Rabbit |
| Buffer: | Serum |
| Tested Applications: | Immunohistochemistry |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Robert J. Denver, PhD, University of Michigan.
References
- Boorse, G.C., Crespi, E.J., Dautzenberg, F.M. and Denver, R.J. (2005) Urocortins from the South African clawed frog Xenopus laevis: Conservation of structure and function in tetrapod evolution. Endocrinology 146:4851-4860 PMID:16037378.
- Distribution in adult Xenopus laevis brain analyzed by immunohistochemistry (neuroanatomical map from Tuinhof R, Ubink R, Tanaka S, Atzori C, van Strien FJ, Roubos EW. Distribution of pro-opiomelanocortin and its peptide end products in the brain and hypophysis of the aquatic toad, Xenopus laevis. Cell Tissue Res. 1998;292(2):251-265).
- Yao, M., Westphal, N. and Denver, R.J. (2004) Neuroanatomical distribution and stressor-induced activation of central corticotropin-releasing factor neurons in Xenopus laevis. Journal of Neuroendocrinology 16:880-893.
- Yao,M., Stenzel-Poore, M. and Denver, R.J. (2007) Structural and functional conservation of vertebrate corticotropin-releasing factor genes: evidence for a critical role for a conserved cyclic AMP response element. Endocrinology 148:2518-2531.
- McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, Thompson LM, Steffan JS, Smith I, Davtyan H, Cahalan M, Cho H, Blurton-Jones M. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nat Commun. 2020 Oct 23;11(1):5370. View article
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