This rabbit IgG polyclonal antibody was raised against C-terminal region of xenopus laevis methyl CpG binding protein 3 (MBD3) and recognizes xenopus methyl-CpG binding protein 3 (MBD3).
Highlights:
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Unlike it's family members MBD3 binds to hydroxymethylated DNA.
From the laboratory of Robert J. Denver, PhD, University of Michigan.
Product Type: | Antibody |
Antigen: | Xenopus methyl-CpG binding protein 3 (MBD3) |
Accession ID: | O95983 |
Isotype: | IgG |
Clonality: | Polyclonal |
Reactivity: | Anuran amphibians, possibly others |
Immunogen: | The unique C-terminal region of Xenopus laevis methyl CpG binding protein 3 (MBD3) was expressed in E. coli and the purified protein was injected into a rabbit for polyclonal antiserum production. AA sequence 6XHis-HVEEISKDGGAPLDKDIDDEEEDQDPREQEADDV |
Species Immunized: | Rabbit |
Buffer: | Serum |
Tested Applications: | Immunohistochemistry |
Storage: | -80C |
Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
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