Mouse monoclonal antibody generated against recombinant IL6 receptor protein.
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Product Type: | Antibody |
Antigen: | IL-6R |
Accession ID: | P05231 |
Host: | Mouse |
Clonality: | Monoclonal |
Clone Name: | 1F3 |
Immunogen: | Recombinant IL6 receptor protein |
Format: | Lyophilized |
Purification Method: | Protein A |
Buffer: | Use 1X PBS as per the concentration required |
Tested Applications: | ELISA (1ug/mL), WB (2ug/mL) |
Storage: | For long term storage store at -20C in small aliquots at a concentration of 0.1mg/ml to 0.5mg/ml to prevent freeze- thaw cycles |
Shipped: | Cold pack |
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