GFP-Caffebody plasmid for the expression of GFP-tagged caffeine-switchable nanobody against mCherry (Chemical-ON switch
Intrabodies are antibodies that work within the cell to bind to an intracellular protein. As such, they can be aimed towards a specific target antigen found in various subcellular locations: cytosol, nucleus, endoplasmic reticulum (ER), mitochondria, peroxisomes, plasma membrane, etc. Their application has been utilized for reserach of several dieseases such as HIV, autoimmune disease, neurodegenerative disease, and transplantation. Caffebody(ies) refers to intrabodies (including both engineered nanobodies and monobodies) that can be controlled by caffeine and its metabolites such as theobromine.
From the laboratory of Yubin Zhou, MD, PhD, Texas A&M University.
Product Type: | Plasmid |
Gene/insert name: | GFP-Caffebody |
Accession ID: | P42212 |
Organism: | Synthetic |
Antibiotic Resistance: | Amp |
Fusion Tag(s): | GFP |
Grow in E. coli at 37 C: | Yes |
Cloning Site 5': | NcoI |
Insert Size: | 2004bp |
Vector Backbone and Size: | pTriEx, 4938bp |
High or low copy: | Low |
Storage: | -20C |
Shipped: | Room temperature |
If you publish research with this product, please let us know so we can cite your paper.