This IgG1 mouse antibody was generated against rat guanine nucleotide-binding protein G(i) subunit alpha-2 (Gi alpha2, or GNAI2) and recognizes rodent and human Gi alpha2 homologs.
Highlights:
Heterotrimeric guanine nucleotide-binding proteins (G-proteins) are a family of proteins consisting of Gα, Gβ, and Gγ subunits. There are four separate subtypes of alpha subunits: i, o, z & t (Gi/o/z/t). Intracellular signaling pathways are activated by Gi/o/z/t in response to activation of cell surface G protein-coupled receptors (GPCRs). GNAI2 gene encodes guanine nucleotide-binding protein G(i), alpha-2 subunit in humans. G(i) proteins play a role in hormonal regulation of adenylate cyclase and possibly in cell division.
From a laboratory at University of Virginia.
Product Type: | Antibody |
Name: | Anti-Rat Gi alpha2 [5C11] Antibody |
Antigen: | Rat Gi alpha2 |
Accession ID: | P04897 |
Molecular Weight: | 41kDa |
Isotype: | IgG1 |
Clonality: | Monoclonal |
Clone Name: | 5C11 |
Reactivity: | Vertebrates |
Immunogen: | Full length, rat Gia2 |
Species Immunized: | Mouse |
Buffer: | PBS, 0.05% Sodium Azide |
Tested Applications: | WB |
Storage: | -20C |
Shipped: | Cold packs |
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