Anti-Nuclear Transport Factor 2 [4F5] Antibody
![Anti-Nuclear Transport Factor 2 [4F5] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-Nuclear Transport Factor 2 [4F5] Antibody")
This mouse IgG2b monocloncal antibody was generated against human Nuclear transport factor 2 (NTF2) and recognizes both human and xenopus NTF2 homologs.
Highlights:
- Reacts with both human and xenopus NTF2 homologs
- Suitable for Western Blot and Immunofluorescence applications
Nucleocytoplasmic transport plays an important role in the regulation of diverse cellular processes, including transcription and translation, growth factor-mediated signaling, stress responses, and cell cycle control. Nuclear transport factor 2 (NTF2) is a soluble transport protein originally identified by its ability to stimulate nuclear localization signal (NLS)-dependent protein import in digitonin-permeabilized cells. NTF2 has been shown to bind nuclear pore complex proteins and the GDP form of Ran in vitro.
From the laboratory of Bryce M. Paschal, PhD, University of Virginia.
This mouse IgG2b monocloncal antibody was generated against human Nuclear transport factor 2 (NTF2) and recognizes both human and xenopus NTF2 homologs.
Highlights:
- Reacts with both human and xenopus NTF2 homologs
- Suitable for Western Blot and Immunofluorescence applications
Nucleocytoplasmic transport plays an important role in the regulation of diverse cellular processes, including transcription and translation, growth factor-mediated signaling, stress responses, and cell cycle control. Nuclear transport factor 2 (NTF2) is a soluble transport protein originally identified by its ability to stimulate nuclear localization signal (NLS)-dependent protein import in digitonin-permeabilized cells. NTF2 has been shown to bind nuclear pore complex proteins and the GDP form of Ran in vitro.
From the laboratory of Bryce M. Paschal, PhD, University of Virginia.
| Product Type: | Antibody |
| Name: | Anti-Nuclear Transport Factor 2 [4F5] Antibody |
| Antigen: | Nuclear transport factor 2 |
| Accession ID: | Q9UKK6 |
| Molecular Weight: | 14kDa |
| Isotype: | IgG2b |
| Clonality: | Monoclonal |
| Clone Name: | 4F5 |
| Reactivity: | Human, mouse, rat, human, monkey, hamster, chicken,xenopus |
| Immunogen: | Recombinant human NTF2 |
| Species Immunized: | Mouse |
| Epitope: | Amino acids 82-169 |
| Purification Method: | Protein A or A/G affinity purified |
| Buffer: | PBS, 0.05% Sodium Azide |
| Tested Applications: | WB, IF |
| Storage: | -20C |
| Shipped: | Cold packs |
- Steggerda SM, Black BE, Paschal BM. Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran. Mol Biol Cell. 2000 Feb;11(2):703-19. doi: 10.1091/mbc.11.2.703. PMID: 10679025; PMCID: PMC14804.
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