Goat Anti-X-arrestin / Arrestin 3 Antibody
This goat IgG polyclonal antibody was generated against peptide sequence C-RKGEEESQKAVE from the C Terminus of arrestin 3 (ARR3) and recognizes human ARR3.
Highlights:
- Reacts with human ARR3
- Suitable for Peptide ELISA and Immunohistochemistry applications
- Mutations are associted with the development of Myopia-26
Arrestins are a family of scaffolding proteins that regulate cell signaling by binding to active G-protein coupled receptors. Arrestin-3 (ARR3) is a non-visual arrestin expressed throughout the body and highly expressed in cone cells and pinealocytes. ARR3 inactivates phosphorylated-opsins, preventing cone signals, and may play a role in the development of Myopia-26 and refractive error.
This goat IgG polyclonal antibody was generated against peptide sequence C-RKGEEESQKAVE from the C Terminus of arrestin 3 (ARR3) and recognizes human ARR3.
Highlights:
- Reacts with human ARR3
- Suitable for Peptide ELISA and Immunohistochemistry applications
- Mutations are associted with the development of Myopia-26
Arrestins are a family of scaffolding proteins that regulate cell signaling by binding to active G-protein coupled receptors. Arrestin-3 (ARR3) is a non-visual arrestin expressed throughout the body and highly expressed in cone cells and pinealocytes. ARR3 inactivates phosphorylated-opsins, preventing cone signals, and may play a role in the development of Myopia-26 and refractive error.
| Product Type: | Antibody |
| Name: | Goat Anti-X-arrestin / Arrestin 3 Antibody |
| Alternative Name(s): | Cone Arrestin, C-arrestin, CAR, Retinal Cone Arrestin-3, X-arrestin |
| Antigen: | X-arrestin / Arrestin 3 |
| Accession ID: | NP_004303.2 |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Reactivity: | Human |
| Specificity: | X-arrestin / Arrestin 3 |
| Immunogen: | CRKGEEESQKAVE |
| Species Immunized: | Goat |
| Epitope: | C Terminus |
| Purification Method: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide |
| Buffer: | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Tested Applications: | Pep-ELISA, IHC |
| Storage: | Aliquot and store at -20C. Minimize freezing and thawing. |
| Shipped: | Cold Packs |
Immunohistochemistry
(4µg/ml) staining of paraffin embedded Human Retina. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry
Negative control showing staining of paraffin embedded Human Retina with no primary antibody.
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