Anti-CD45 [I3/2.3] Hybridoma
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This hybridoma line produces a rat anti-mouse CD45 monoclonal antibody (I3/2.3).
CD45 is a type 1 transmembrane protein tyrosine phosphatase expressed by all haematopoietic stem cells except erythrocytes and platelets. CD45 is needed for the activation and suppression of T cells after interacting with antigen-presenting cells. CD45 regulates T cell activation by gatekeeping antigen presentation and filtering based on binding strength.
This hybridoma line produces a rat anti-mouse CD45 monoclonal antibody (I3/2.3).
CD45 is a type 1 transmembrane protein tyrosine phosphatase expressed by all haematopoietic stem cells except erythrocytes and platelets. CD45 is needed for the activation and suppression of T cells after interacting with antigen-presenting cells. CD45 regulates T cell activation by gatekeeping antigen presentation and filtering based on binding strength.
Specifications
| Product Type: | Antibody |
| Name: | Anti-CD45 [I3/2.3] Hybridoma |
| Cell Type: | Hybridoma Cell Line |
| Antigen: | CD45 |
| Isotype: | IgG2b |
| Clonality: | Monoclonal |
| Clone Name: | I3/2.3 |
| Reactivity: | Mouse |
| Specificity: | CD45 |
| Immunogen: | T1M1 (Thy-1-c) cells |
| Growth Conditions: | Dulbecco's Modified Eagles medium (DMEM) + 10% fetal bovine serum (FBS) + non-essential amino acid + sodium pyruvate + 50uM beta-mercaptoethanol |
| Cryopreservation: | Resuspend cells in DMEM, 20% FBS, and 10% DMSO. Store in liquid nitrogen. |
| Species Immunized: | Rat |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
References
- J. Exp. Med. (1978) 148:313-323
- Eng. Med, Biol. Soc.(2011) 2011:2957-60
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