This antibody is specific to a Human NPC1 fragment conjugated to a carrier protein.
Niemann-Pick disease type C1 is a lysosomal storage disease caused by a mutation in the NPC1 gene. NPC1 encodes an integral membrane protein containing sequence motifs thought to be consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations. Mutations in NPC1 have also been linked with obesity, HIV-AIDS, and Ebola virus.
From the laboratory of Yiannis Ioannou, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
Product Type: | Antibody |
Name: | Anti NPC1 monoclonal antibody (17B5) |
Accession ID: | Q9UHC9 |
Host: | Mouse |
Isotype: | IgG1 |
Clonality: | Monoclonal |
Clone Name: | 17B5 |
Specificity: | This antibody recognizes Human NPC1 |
Immunogen: | Human NPC-1 fragment conjugated to a carrier protein |
Format: | Liquid |
Purification Method: | Protein G purified |
Buffer: | PBS, 0.05% (w/v) Sodium Azide |
Tested Applications: | WB |
Storage: | Store at 4C |
Shipped: | Cold packs |
If you publish research with this product, please let us know so we can cite your paper.