Anti-MAP2 [AA6] Antibody
This IgG2a mouse antibody was generated against taxol-stabalized microtubules from rat brain and recognizes mammalian homologs of MAP2.
Microtubules (MTs) are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. Microtubule-associated proteins (MAPs) bind to the tubulin subunits that make up microtubules to regulate their stability.
MAP2 serves to stabilize MT growth by crosslinking MT with intermediate filaments and other MT.
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
Part of The Investigator's Annexe program.
This IgG2a mouse antibody was generated against taxol-stabalized microtubules from rat brain and recognizes mammalian homologs of MAP2.
Microtubules (MTs) are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. Microtubule-associated proteins (MAPs) bind to the tubulin subunits that make up microtubules to regulate their stability.
MAP2 serves to stabilize MT growth by crosslinking MT with intermediate filaments and other MT.
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Name: | Anti-MAP2 (AA6) Monoclonal Antibody |
| Accession ID: | P11137 |
| Host: | mouse |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | AA6 |
| Specificity: | Recognizes mammalian homologs of MAP2 |
| Immunogen: | Generated against taxol-stabalized microtubules from rat brain |
| Format: | Liquid |
| Purification Method: | Protein G affinity purified |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, IHC, IP, IF |
| Concentration: | 1mg/mL |
| Amount: | 100uL |
| Storage: | Store at 4C |
| Shipped: | Cold packs |
| Immunoblots of P9 quail and adult rat brain microtubule proteins stained with monoclonal antibodies and polyclonal antisera to MAP2. Molecular weights are indicated by dashes at the far right (kDa). Monoclonal antibody AA6 stains the HMW MAP2 doublet (MAP2a and MAP2b) in the rat preparation and a single band with an apparent molecular weight of 260 kDa on quail microtubule immunoblots. Adapted from: Tucker RP, Binder LI, Viereck C, Hemmings BA, Matus AI. The sequential appearance of low- and high-molecular-weight forms of MAP2 in the developing cerebellum. J Neurosci, 8(12):4503-4512, (1988).
Provider
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
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