Anti-MUC18 (CD146) [OJ79c] Antibody
This monoclonal antibody was generated against a recombinant MUC18 (D1-D5) Fc chimeric protein and recognizes human MUC18.
MUC18 (also known as CD146, melanoma cell adhesion molecule or MCAM) is a cell adhesion molecule that belongs to the immunoglobulin superfamily and is used as a marker for endothelial cell lineage. MUC18 is overexpressed in certain lesions such as melanoma, where increased expression has been shown to correlate inversely with patient prognosis.
From a laboratory at Cancer Research Technology, Cancer Research Technology.
Part of The Investigator's Annexe program.
This monoclonal antibody was generated against a recombinant MUC18 (D1-D5) Fc chimeric protein and recognizes human MUC18.
MUC18 (also known as CD146, melanoma cell adhesion molecule or MCAM) is a cell adhesion molecule that belongs to the immunoglobulin superfamily and is used as a marker for endothelial cell lineage. MUC18 is overexpressed in certain lesions such as melanoma, where increased expression has been shown to correlate inversely with patient prognosis.
From a laboratory at Cancer Research Technology, Cancer Research Technology.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Antigen: | MUC18 (CD146, MCAM) |
| Accession ID: | P43121 |
| Molecular Weight: | ~113 kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | OJ79c |
| Reactivity: | Human |
| Immunogen: | Recombinant MUC18 (D1-D5) Fc chimeric protein |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | FACS, IHC, IHC-Frozen |
| Concentration: | 1 mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
Provider
From a laboratory at Cancer Research Technology, Cancer Research Technology.
References
- Kuzu I, Bicknell R, Fletcher CD, Gatter KC. Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors. Lab Invest. 1993 Sep;69(3):322-8. PMID: 7690867
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