pNCA-C-SNH Moloney Murine Leukemia Virus (M-MuLV) Plasmid
This plasmid pNCA-C-SNH encodes for the entire proviral genome of Moloney murine leukemia virus (Shinnick sequence).
Highlights
- Difference from WT is the presence of a linker insertion at the C terminal region of pol gene resulting in premature truncation of the integrase protein by 28 amino acids
- C terminus of the pol gene has a NheI restriction site, which allows for introduction of fusion tags
Murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in mouse hosts.
Also available: pNCA-C-XN Moloney Murine Leukemia Virus (M-MuLV) Plasmid
From the laboratory of Monica J. Roth, PhD, Rutgers University
Part of The Investigator's Annexe program.
This plasmid pNCA-C-SNH encodes for the entire proviral genome of Moloney murine leukemia virus (Shinnick sequence).
Highlights
- Difference from WT is the presence of a linker insertion at the C terminal region of pol gene resulting in premature truncation of the integrase protein by 28 amino acids
- C terminus of the pol gene has a NheI restriction site, which allows for introduction of fusion tags
Murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in mouse hosts.
Also available: pNCA-C-XN Moloney Murine Leukemia Virus (M-MuLV) Plasmid
From the laboratory of Monica J. Roth, PhD, Rutgers University
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Plasmid |
| Antibiotic Resistance: | Amp |
| Grow in E. coli at 37 C: | Yes |
| Vector Backbone and Size: | 11095 bp |
| Storage: | 4C |
| Shipped: | Ambient temperature, spotted filter paper |
Provider
From the laboratory of Monica J. Roth, PhD, Rutgers University
References
- Roth MJ. Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein. J Virol. 1991 Apr;65(4):2141-5.
- Aiyer S, Swapna GV, Malani N, Aramini JM, Schneider WM, Plumb MR, Ghanem M, Larue RC, Sharma A, Studamire B, Kvaratskhelia M, Bushman FD, Montelione GT, Roth MJ. NLS-dependent nuclear localization of p120ctn is necessary to relieve Kaiso-mediated transcriptional repression. (2004) J. Cell Sci. 117: 2675-2686
If you publish research with this product, please let us know so we can cite your paper.
