Anti-Tau [PC1C6] Antibody
This IgG2a mouse antibody was generated against purified denatured bovine microtubule associated proteins (MAPs) and recognizes human, rat, and bovine Tau1.
Highlights:
- Reacts with human, rat, and bovine Tau1
- Suitable for Western Blot and Immunohistochemistry applications
Recombinant versions available from our sister company, Absolute Antibody:
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma PC1C6
Tau protein is a highly soluble microtubule-associated protein. In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. The protein interacts with tubulin to stabilize microtubules and promote tubulin assembly into microtubules. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.
From the laboratory of Lester I. Binder, PhD, University of Virginia.
This IgG2a mouse antibody was generated against purified denatured bovine microtubule associated proteins (MAPs) and recognizes human, rat, and bovine Tau1.
Highlights:
- Reacts with human, rat, and bovine Tau1
- Suitable for Western Blot and Immunohistochemistry applications
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma PC1C6
Recombinant versions available from our sister company, Absolute Antibody:
Tau protein is a highly soluble microtubule-associated protein. In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. The protein interacts with tubulin to stabilize microtubules and promote tubulin assembly into microtubules. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.
From the laboratory of Lester I. Binder, PhD, University of Virginia.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Name: | Anti-Tau [PC1C6] |
| Antigen: | Tau1 protein |
| Accession ID: | P10636 |
| Isotype: |
EG7001: IgG2a Recombinant versions: see product name |
| Clonality: | Monoclonal |
| Clone Name: | PC1C6 |
| Reactivity: | Recognizes human, rat, and bovine Tau1 |
| Immunogen: | Generated against purified denatured bovine microtubule associated proteins |
| Species Immunized: | balb/c mouse |
| Purification Method: | Protein G affinity purified |
| Buffer: |
EG7001: PBS, 0.05% (w/v) Sodium Azide Recombinant versions: PBS with 0.02% Proclin 300 |
| Tested Applications: | WB,IHC |
| Concentration: | 1 mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
- Binder LI, Frankfurter A, and Rebhun LI. The distribution of Tau in mammalian central nervous system. J Cell Biol. 101(4):1371-8 (1985).
If you publish research with this product, please let us know so we can cite your paper.
