Anti-IL-2RB (CD122) [5H4] Antibody
This rat IgG2a monoclonal antibody was raised against rat YB2/0 cell line expressing truncated IL-2Rβ and is specific for mouse Interleukin 2 receptor beta chain (IL-2Rβ).
Highlights:
- Reacts with mouse IL-2Rβ
Recombinant versions available from our sister company, Absolute Antibody:
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma 5H4.
The 5H4 antibody reacts with mouse CD122, the 90-110 kDa interleukin-2 receptor beta chain. CD122 is expressed by NK cells and some T cells in the periphery and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to CD122 is not inhibited by the 5H4 antibody.
From the laboratory of Thomas R. Malek, PhD, University of Miami.
This rat IgG2a monoclonal antibody was raised against rat YB2/0 cell line expressing truncated IL-2Rβ and is specific for mouse Interleukin 2 receptor beta chain (IL-2Rβ).
Highlights:
- Reacts with mouse IL-2Rβ
Recombinant versions available from our sister company, Absolute Antibody:
- Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e., specificity) from the hybridoma 5H4.
The 5H4 antibody reacts with mouse CD122, the 90-110 kDa interleukin-2 receptor beta chain. CD122 is expressed by NK cells and some T cells in the periphery and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to CD122 is not inhibited by the 5H4 antibody.
From the laboratory of Thomas R. Malek, PhD, University of Miami.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Name: | Anti-IL-2RB (CD122) [5H4] Antibody |
| Antigen: | IL-2Rβ |
| Accession ID: | P16297 |
| Molecular Weight: | 70-85kDa |
| Isotype: |
EMI024: IgG2a Recombinant versions: see product name |
| Clonality: | Monoclonal |
| Clone Name: | 5H4 |
| Reactivity: | Mouse |
| Species Immunized: | Lewis Rat |
| Purification Method: | Protein G |
| Buffer: |
EMI024: PBS, 0.05% (w/v) Sodium Azide Recombinant versions: PBS with 0.02% Proclin 300 |
| Storage: | -20C |
| Shipped: | Cold Packs |
- Malek TR, Furse RK, Fleming ML, Fadell AJ, He YW. Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits. J Interferon Cytokine Res. 1995 May;15(5):447-54. PubMed PMID: 7648447.
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