KLF4 (EF1A) Lentivirus
Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells, and in preventing their differentiation.
This premade lentivirus includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction and expression of the target genes as well as antibiotics resistant genes or reporters. A woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is believed to promote RNA processing events and nuclear export, boosting expression of your gene of interest in target cells by facilitating the production of mature mRNA from transcripts initiated by the virus's internal promoter (e.g. pCMV).
Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells, and in preventing their differentiation.
This premade lentivirus includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction and expression of the target genes as well as antibiotics resistant genes or reporters. A woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is believed to promote RNA processing events and nuclear export, boosting expression of your gene of interest in target cells by facilitating the production of mature mRNA from transcripts initiated by the virus's internal promoter (e.g. pCMV).
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Virus |
| Product MPN: | PLV-10011-50 |
| Biosafety Level: | BSL-2 |
| Vector Information: | Vector includes both 5? and 3? lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Target Gene / Reporter(s): | human KLF4 |
| Promoter: | EF1A |
| Selection Gene: | puromycin |
| Virus: | LV-EF1A-KLF4 |
| Titer: | 1 x 10^8CFU/ml |
| Storage: | Store at -80C. Multiple freeze/thaw cycles not recommended. |
| Shipped: | Dry ice |
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