Recombinant p65-GST Protein
This protein has a GST fusion tag for efficient immunodetection.
p65 (reticuloendotheliosis viral oncogene homolog A, RelA) is a subunit of NF-κB. NF-κB is a pleiotropic transcription factor present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κB is a homo- or heterdimeric complex formed by Rel family subunits. p65 (RelA) can homodimerize or form heterodimeric complexes with p50, c-Rel, and p52.
From the laboratory of Lawrence Pfeffer, PhD, University of Tennessee.
This protein has a GST fusion tag for efficient immunodetection.
p65 (reticuloendotheliosis viral oncogene homolog A, RelA) is a subunit of NF-κB. NF-κB is a pleiotropic transcription factor present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κB is a homo- or heterdimeric complex formed by Rel family subunits. p65 (RelA) can homodimerize or form heterodimeric complexes with p50, c-Rel, and p52.
From the laboratory of Lawrence Pfeffer, PhD, University of Tennessee.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Protein |
| Name: | Recombinant p65-GST Protein; GST fusion protein of Mus musculus p65 (reticuloendotheliosis viral oncogene homolog A, RelA) |
| Accession ID: | Q04206 |
| Source: | Expressed in E. coli |
| Molecular Weight: | ~90kDa |
| Amino Acid Sequence: | MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPTRRIAVPTRNSTSVPKPAPQPYTFPASLSTINFDEFSPMLLPSGQISNQALALAPSSAPVLAQTMVPSSAMVPLAQPPAPAPVLTPGPPQSLSAPVPKSTQAGEGTLSEALLHLQFDADEDLGALLGNSTDPGVFTDLASVDNSEFQQLLNQGVSMSHSTAEPMLMEYPEAITRLVTGSQRPPDPAPTPLGTSGLPNGLSGDEDFSSIADMDFSALLSQISS |
| Fusion Tag(s): | GST |
| Purity: | ~85% by SDS-PAGE gel |
| Buffer: | dH20 |
| Concentration: | 100 ng/ul |
| Storage: | Store at -80C |
| Shipped: | Dry ice |
Provider
From the laboratory of Lawrence Pfeffer, PhD, University of Tennessee.
References
- Yang, C.H., Murti, A., & Pfeffer, L.M. IFN induces NIK/TRAF-dependent NF-kB activation to promote cell survival. J. Biol. Chem. 280: 31530-31536 (2005)
- Gupte TM, Ritt M, Dysthe M, Malik RU, Sivaramakrishnan S. Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling. Nat Commun. 2019;10(1):4836. Published 2019 Oct 23. View article
If you publish research with this product, please let us know so we can cite your paper.
