N-MYC (CMV) Lentivirus
MYC is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Amplification of N-Myc is associated with a variety of tumors, most notably neuroblastomas.
This premade lentivirus includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction and expression of the target genes as well as antibiotics resistant genes or reporters. A woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is believed to promote RNA processing events and nuclear export, boosting expression of your gene of interest in target cells by facilitating the production of mature mRNA from transcripts initiated by the virus's internal promoter (e.g. pCMV).
This lentivirus expressses N-Myc under the control of the CMV promoter.
MYC is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Amplification of N-Myc is associated with a variety of tumors, most notably neuroblastomas.
This premade lentivirus includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction and expression of the target genes as well as antibiotics resistant genes or reporters. A woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is believed to promote RNA processing events and nuclear export, boosting expression of your gene of interest in target cells by facilitating the production of mature mRNA from transcripts initiated by the virus's internal promoter (e.g. pCMV).
This lentivirus expressses N-Myc under the control of the CMV promoter.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Virus |
| Product MPN: | PLV-10018-50 |
| Vector Information: | Vector includes both 5? and 3? lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Target Gene / Reporter(s): | N-MYC |
| Promoter: | CMV |
| Selection Gene: | Puromycin |
| Virus: | LV-CMV-N-MYC |
| Titer: | 1 x 10^7-8 CFU/ml |
| Storage: | Store at -80C. Multiple freeze/thaw cycles not recommended. |
| Shipped: | Dry ice |
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