Pyrene azide 1
This azide contains hydrophilic triethyleneglycol linker to mitigate intrinsic pyrene hydrophobicity, and facilitate attachment to biomolecules in aqueous solutions.
Pyrene is a polyaromatic hydrocarbon with strong short-wavelength fluorescence. Unlike other fluorescent dyes, polyaromatic hydrocarbons are fluorescent probes with strong sensitivity to microenvironment. Thus, its fluorescence is different in polar, and nonpolar environments. Other effects can also be observed.
When two pyrenes are in close proximity, they form excimers. Excimer formation can be easily observed, and quantitatively estimated using fluorescent spectra.
Pyrene azide is a reagent for easy pyrene Click Chemistry labeling of any alkyne-bearing molecule. It allows to turn any molecule into pyrene-bearing probe.
This azide contains hydrophilic triethyleneglycol linker to mitigate intrinsic pyrene hydrophobicity, and facilitate attachment to biomolecules in aqueous solutions.
Pyrene is a polyaromatic hydrocarbon with strong short-wavelength fluorescence. Unlike other fluorescent dyes, polyaromatic hydrocarbons are fluorescent probes with strong sensitivity to microenvironment. Thus, its fluorescence is different in polar, and nonpolar environments. Other effects can also be observed. When two pyrenes are in close proximity, they form excimers. Excimer formation can be easily observed, and quantitatively estimated using fluorescent spectra. Pyrene azide is a reagent for easy pyrene Click Chemistry labeling of any alkyne-bearing molecule. It allows to turn any molecule into pyrene-bearing probe.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Small Molecule |
| Name: | Pyrene azide 1 |
| Molecular Weight: | 402.45 |
| Variant MPN: | B1530 |
| Format: | yellow powder |
| Purity: | 95+% (NMR), pure (TLC), passed functional test (reaction with amine) |
| Solubility: | Good in organic solvents; poor in water |
| Stability: | Fluorescence degrades with prolonged exposure to light |
| Spectral Information: | Pyrene excitation maximum: 240, 273, 335nmPyrene extinction at max excitation: 83,000; 53,000; 55,000Pyrene emission maximum: 380nmPyrene fluorescence quantum yield: 0.3 |
| Storage: | Store at -20°C in the dark |
| Shipped: | Ambient temperature |
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