Cy5 hydrazide
Cy5 hydrazide reactive dye for the labeling of aldehydes and ketones.
This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, and oligonucleotides with aldehyde moieties.
Also available: Cy5 Boc-hydrazide (with Boc protective group, which can be removed with acid).
Cy5 hydrazide reactive dye for the labeling of aldehydes and ketones.
This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, and oligonucleotides with aldehyde moieties.
Also available: Cy5 Boc-hydrazide (with Boc protective group, which can be removed with acid).
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Small Molecule |
| Name: | Cy5 hydrazide |
| Molecular Weight: | 569.61 |
| Variant MPN: | 13070 |
| Format: | dark blue solid |
| Purity: | 95+% (NMR), passed the functional test (reaction with ketone) |
| Solubility: | 625uM in water (0.36 mg/mL) and 100uM in pH 7 phosphate buffer (0.056 mg/mL) |
| Stability: | Fluorescence degrades with prolonged exposure to light |
| Spectral Information: | Cy5 excitation maximum: 646nmCy5 extinction at max excitation: 250,000Cy5 emission maximum: 662nmCy5 fluorescence quantum yield: 0.2 |
| Storage: | Store at -20°C in the dark. Dessicate |
| Shipped: | Ambient temperature |
Comments
Can replace Alexa Fluor 647 or DyLight 652
References
1. Cohen DT, Wales TE, McHenry MW, Engen JR, Walensky LD. Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX. Cell Rep. 2020;30(10):3229-3239.e6. View article
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