Trans-Cyclooctene (TCO)-NHS ester is an amine-reactive building block used to derivatize primary amine-containing molecules with a TCO moiety.
Highlights:
TCO-NHS ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. Short spacer arm adds minimal mass to modified molecules (153.2 daltons).
Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
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Product Type: | Small Molecule |
Name: | Trans-Cyclooctene (TCO)-NHS Ester |
Chemical Formula: | C13H17NO5 |
Molecular Weight: | 267.28 |
Variant MPN: | 1016 |
Purity: | >90% H NMR |
Solubility: | DCM, Chloroform, DMSO, DMF |
Storage: | -20C.Desiccate |
Shipped: | Frozen - Dry Ice |
Applications: Protein-protein conjugation, protein-antibody conjugation, protein-small molecule conjugation, 18F radiolabeling, protein-oligonucleotide conjugation, surface modification
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