NANOG_h (EF1A) Lentivirus
NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.
Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used to drive ectopic gene expression in various in vitro and in vivo contexts. EF-1 alpha (or EF1a) is often useful in conditions where other promoters (such as CMV) have diminished activity or have been silenced (as in embryonic stem cells).
NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture.
Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used to drive ectopic gene expression in various in vitro and in vivo contexts. EF-1 alpha (or EF1a) is often useful in conditions where other promoters (such as CMV) have diminished activity or have been silenced (as in embryonic stem cells).
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Virus |
| Product MPN: | PLV-10075-50 |
| Biosafety Level: | BSL-2 |
| Vector Information: | Vector includes both 5? and 3? lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Target Gene / Reporter(s): | NANOG_h |
| Promoter: | EF1A |
| Selection Gene: | Puromycin |
| Titer: | 1 x 10^8TU/mL |
| Storage: | Store at -80C. Multiple freeze/thaw cycles not recommended. |
| Shipped: | Dry ice |
Documentation
References
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