Cy5-Maleimide

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
FLP169
Cy5 maleimide, 25 mg
25mg In stock
Regular Price:$448.00
On Sale:
FLP170
Cy5 maleimide, 50 mg
50mg In stock
Regular Price:$783.00
On Sale:
FLP167
Cy5 maleimide, 1 mg
1mg In stock
Regular Price:$124.00
On Sale:
FLP168
Cy5 maleimide, 5 mg
5mg In stock
Regular Price:$232.00
On Sale:
Specifications

Product Type: Small Molecule
Chemical Formula: C38H45ClN4O3
CAS number: N/A
Molecular Weight: 641.24
Extinction Coefficient: 250000
Variant MPN: 13080
Format: Dark blue powder
Purity: NMR 1H, HPLC-MS (95%)
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), insoluble in water
Ex/Em Maxima: 646/662 nm
Quantum Yield: 0.2
Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
Shipped: Ambient temperature

References
  1. Noriega, R.; Finley, D.T.; Haberstroh, J.; Geissler, P.L.; Francis, M.B.; Ginsberg, N.S. Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity. The Journal of Physical Chemistry B, 2015, 119(23), 6963-6973.
  2. Leonard, J.D.; Narlikar, G.J. A Nucleotide-Driven Switch Regulates Flanking DNA Length Sensing by a Dimeric Chromatin Remodeler. Molecular Cell, 2015, 57(5), 850-859.
  3. Popp, M.W. Site-Specific Labeling of Proteins via Sortase: Protocols for the Molecular Biologist. Methods in Molecular Biology, 2015, 1266, 185-198.
  4. Lipchik, A.M.; Perez, M.; Cui, W.; Parker, L.L. Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities. Analytical Chemistry, 2015, 87(15), 7555-7558.
  5. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512.
  6. Damayanti, N.P.; Parker, L.L.; Irudayaraj, J.M.K. Fluorescence Lifetime Imaging of Biosensor Peptide Phosphorylation in Single Live Cells. Angewandte Chemie International Edition, 2013, 52(14), 3931-3934
  7. Hartley, M.D.; Schneggenburger, P.E.; Imperiali, B. Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities. Proceedings of the National Academy of Sciences of the U.S.A., 2013, 110(52), 20863-20870.
  8. Madamba EV, Berthet EB, Francis NJ. Inheritance of Histones H3 and H4 during DNA Replication In Vitro. Cell Rep. 2017 Oct 31;21(5):1361-1374. View Article

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