Phosphate CPG solid support
Phosphate CPG is a solid support for the synthesis of 3'-phosphorylated oligonucleotides.
The phosphate group can be used as a blocking functionality to prevent 3'-5' exonuclease activity of some polymerases.
Upon cleavage from the support, a phosphate group remains at the 3' end of the oligonucleotide. It does not require any changes in oligo synthesis and deprotection protocols.
Phosphate CPG is a solid support for the synthesis of 3'-phosphorylated oligonucleotides.
The phosphate group can be used as a blocking functionality to prevent 3'-5' exonuclease activity of some polymerases. Upon cleavage from the support, a phosphate group remains at the 3' end of the oligonucleotide. It does not require any changes in oligo synthesis and deprotection protocols.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Small Molecule |
| Variant MPN: | 13860 |
| Format: | off-white beads |
| Purity: | NMR 1H, HPLC-MS (95%) of bound reagent, loading measurement, functional testing (oligo synthesis) |
| Comments: |
Pore size: 50 nm Typical loading, umol/g: 70-90 Coupling conditions: standard coupling, identical to normal nucleobases Cleavage conditions: ammonia, 2 h at room temperature Deprotection conditions: identical to protected nucleobases |
| Storage: | 24 months after receival at -20°C in the dark. |
| Shipped: | room temperature |
References
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