Anti-Influenza A H1N1, Nucleoprotein (NP) Antibodies
These mouse monoclonal antibodies were raised against the NP of H3N2 virus A/Minnesota/11/2010.
Highlights:
- Broadly react with the NP of all tested subtypes of Influenza A viruses
- Antibody G20 has strong reactivity with the NP of equine H3N8 virus
Influenza A viruses are the most common causes for human respiratory diseases, resulting in millions of severe illness cases and ~250,000-500,000 deaths throughout the world each year. Nucleoprotein (NP) is the most abundant and conserved influenza protein, its primary function is to encapsidate the virus genome for RNA transcription, replication and packaging. The broad-reactivity of NP monoclonal antibodies bestow their value for scientific research and clinical diagnosis of influenza virus infection.
From the laboratory of Hongquan Wan, DVM, PhD, Food and Drug Administration.
These mouse monoclonal antibodies were raised against the NP of H3N2 virus A/Minnesota/11/2010.
Highlights:
- Broadly react with the NP of all tested subtypes of Influenza A viruses
- Antibody G20 has strong reactivity with the NP of equine H3N8 virus
Influenza A viruses are the most common causes for human respiratory diseases, resulting in millions of severe illness cases and ~250,000-500,000 deaths throughout the world each year. Nucleoprotein (NP) is the most abundant and conserved influenza protein, its primary function is to encapsidate the virus genome for RNA transcription, replication and packaging. The broad-reactivity of NP monoclonal antibodies bestow their value for scientific research and clinical diagnosis of influenza virus infection.
From the laboratory of Hongquan Wan, DVM, PhD, Food and Drug Administration.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Accession ID: | P03466 |
| Isotype: | G20: IgG2bA40:IgG1A60: IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | G20A40A60 |
| Reactivity: | Reacts with the nucleoprotein (NP) of all tested influenza A viruses |
| Immunogen: | Influenza A H3N2 virus A/Minnesota/11/2010 |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Storage: | -20C |
| Shipped: | Cold Packs |
- Wan H, Yang H, Shore DA, Garten RJ, Couzens L, Gao J, Jiang L, Carney PJ, Villanueva J, Stevens J, Eichelberger MC. Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers. Nat Commun. 2015 Feb 10;6:6114.
- Karim M, Biquand E, Declercq M, Jacob Y, van der Werf S, Demeret C. Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases. mBio. 2020;11(2):e00305-20. Published 2020 Apr 7. View article
- Blanchard EL, Vanover D, Bawage SS, Tiwari PM, Rotolo L, Beyersdorf J, Peck HE, Bruno NC, Hincapie R, Michel F, Murray J, Sadhwani H, Vanderheyden B, Finn MG, Brinton MA, Lafontaine ER, Hogan RJ, Zurla C, Santangelo PJ. Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents. Nat Biotechnol. 2021 Feb 3. View article
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