KPCY Mouse Pancreatic Cancer Cell Lines
Pancreatic cancer cell lines from primary tumors derived from KPCY mice.
Highlights
- Derived from autochthonous KPC mouse model of pancreatic ductal adenocarcinoma (PDA) - Recapitulates major features of the human disease, including mutated Kras and p53
- Tool for identifying new targets responsible for thwarting responses to immunotherapy in resistant tumors
Pancreatic ductal adenocarcinoma (PDA) is a type of exocrine pancreatic cancer. It is the most common type of pancreatic cancer. 95% of all pancreatic cancers are PDA. PDA develops from cells lining small tubes in the pancreas called ducts. These carry the digestive juices, which contain enzymes, into the main pancreatic duct and then on into the duodenum. PDA can grow anywhere in the pancreas, though it is most often found in the head of the pancreas.
From the laboratory of Ben Z. Stanger, MD, PhD, University of Pennsylvania.
Pancreatic cancer cell lines from primary tumors derived from KPCY mice.
Highlights
- Derived from autochthonous KPC mouse model of pancreatic ductal adenocarcinoma (PDA) - Recapitulates major features of the human disease, including mutated Kras and p53
- Tool for identifying new targets responsible for thwarting responses to immunotherapy in resistant tumors
Pancreatic ductal adenocarcinoma (PDA) is a type of exocrine pancreatic cancer. It is the most common type of pancreatic cancer. 95% of all pancreatic cancers are PDA. PDA develops from cells lining small tubes in the pancreas called ducts. These carry the digestive juices, which contain enzymes, into the main pancreatic duct and then on into the duodenum. PDA can grow anywhere in the pancreas, though it is most often found in the head of the pancreas.
From the laboratory of Ben Z. Stanger, MD, PhD, University of Pennsylvania.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
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| Product Type: | Cell Line |
| Cell Type: | Pancreatic cancer cell |
| Organism: | Mouse |
| Source: | Mouse pancreatic cancer |
| Morphology: | Epithelial |
| Biosafety Level: | BSL1 |
| Subculturing: | Doubling time ~ 16hours |
| Growth Conditions: | DMEM + 10% FBS + Glutamax |
| Cryopreservation: | Growth medium + 10% DMSO |
| Donor Attributes: | Sex: MH6419 (F); MH6620 (F); MH6499 (F); MH6421 (F); MH6694 (F); MH5821 (F); MH2838 (F); MH2699 (M); MH6422 (M); MH6555 (M); MH6556 (M); MN7160 (M); MH7062 (M) |
| Mycoplasma Tested: | Yes; Also tested for mouse pathogens (See: KPCY Pathogen Testing Results) |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
- Li, Jinyang, et al. "Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy." Immunity 49.1 (2018): 178-193.
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